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ADHD is associated with an earlier age at onset of substance use and a higher likelihood of use of a variety of substances. 17, - 19 Brook et al 20 reported that the diagnosis of ADHD poses an increased risk of SUD into adulthood; meeting criteria for a diagnosis of ADHD in adolescence is associated with developing SUDs in a subject's 20s and 30s. . Among individuals with ADHD, the number.